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High blood pressure during pregnancy

Figure 1 Previous studies have established that patients affected by PCOS with BMI in the highest quartile (30 Kg/m 2 ) have a very high risk of developing MS ( PCOS is often accompanied with altered gonadotropin levels, decreased levels of IGF-BP1, increased ovarian 17-hydroxiprogesterone (17-OHP) and androgen response to Gonadotropin-Releasing-Hormone agonists (GnRH-agonists)

This restricts infection until adaptive immunity kicks in

Regulates matrixcell tension: By improving extracellular matrix organization, GHK reduces the mechanical cues that sustain myofibroblast contractility